A multi objective model for maximizing immunogenicity level of vaccination while minimizing cost and extra-immunization

Document Type : Research Article


School of Industrial Engineering, Iran University of Science and Technology, Tehran, Iran


Mortality decrease due to immunizing is the achievement of vaccination. Immunizing faces challenges: Immunogenicity level, cost and extra-immunization. To overcome these a multi-objective Maximizing Immunogenicity, minimizing Cost and Extra-immunization model with Different Vaccine Formulary (ICEDVF) is introduced. Usually, Costs and budget lead to incomplete immunizing. Providing concept of immunogenicity under a fixed budget, the ICEDVF model seeks vaccines maximize immunogenicity and minimize both cost and extra immunization. The augmented e-constraint method is applied to solve ICEDVF and the results are presented for the U.S.